NDLI: Genes that mediate breast cancer metastasis to lung

Content Provider	Semantic Scholar
Author	Minn, Andy J. Gupta, Gaorav P. Siegel, Peter M. Bos, Paula D. Shu, Weiping Giri, Dilip D. Viale, Agnes J. Olshen, Adam B. Gerald, William L. Massagué, Joan
Copyright Year	2005
Abstract	By means of in vivo selection, transcriptomic analysis, functional verification and clinical validation, here we identify a set of genes that marks and mediates breast cancer metastasis to the lungs. Some of these genes serve dual functions, providing growth advantages both in the primary tumour and in the lung microenvironment. Others contribute to aggressive growth selectively in the lung. Many encode extracellular proteins and are of previously unknown relevance to cancer metastasis.
Starting Page	518
Ending Page	524
Page Count	7
File Format	PDF HTM / HTML
DOI	10.1038/nature03799
PubMed reference number	16049480
Journal	Medline
Volume Number	436
Alternate Webpage(s)	http://www.nature.com/nature/journal/v436/n7050/pdf/nature03799.pdf
Alternate Webpage(s)	https://doi.org/10.1038/nature03799
Journal	Nature
Language	English
Access Restriction	Open
Content Type	Text
Resource Type	Article

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