NDLI: Antigenemia y reacción de polimerasa en cadena en tiempo real en el diagnóstico de enfermedad por citomegalovirus en adultos con virus de inmunodeficiencia adquirida

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Antigenemia y reacción de polimerasa en cadena en tiempo real en el diagnóstico de enfermedad por citomegalovirus en adultos con virus de inmunodeficiencia adquirida

Content Provider	Semantic Scholar
Author	Luchsinger, Vivían Vásquez, Patricia Torres Silva, Matías Bruno, Marco J. Siches, Izkia Villarroel, Javier Garmendia, María Luisa Larrañaga, Carmen Larrañaga
Copyright Year	2015
Abstract	BACKGROUND: Cytomegalovirus (CMV) infection is frequent in HIV adults. It is unknown usefulness of quantitative methods for diagnosing the CMV disease in Chilean patients. AIM: To determine the performance of antigenemia and real time polymerase chain reaction (rtPCR) in the diagnosis of CMV disease in Chilean HIV adults. METHOD: Detection of CMV by viral isolation (AVR) antigenemia and quantitative rtPCR in HIV adults. RESULTS: The 102 adults with suspected CMV disease had lower LTCD4 count and higher HIV viral load than 77 patients without suspicion (p /= lcell (+) and >/= 5.5 log10 copies/2 x 10(6) cells. CMV was isolated in 6/179 patients (3.4%) all symptomatic. CONCLUSION: Positivity of antigenemia and rtPCR are similar for diagnosing CMV disease in Chilean HIV adults. AVR is inappropriate as a gold standard for its low performance.
Starting Page	664
Ending Page	671
Page Count	8
File Format	PDF HTM / HTML
DOI	10.4067/S0716-10182015000700008
Volume Number	32
Alternate Webpage(s)	https://scielo.conicyt.cl/pdf/rci/v32n6/art08.pdf
Alternate Webpage(s)	https://doi.org/10.4067/S0716-10182015000700008
Language	English
Access Restriction	Open
Content Type	Text
Resource Type	Article

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