Loading...
Please wait, while we are loading the content...
Similar Documents
Highly Efficient Synthesis of Trisubstituted Pyrazoles and Disubstituted Isoxazoles via Intramolecular Wittig Reactions: a Diversity-oriented Synthesis of Heteroarene Scaffolds
| Content Provider | Semantic Scholar |
|---|---|
| Author | Khairnar, Pankaj V. Lin, Wenwei |
| Copyright Year | 2019 |
| Abstract | An efficient protocol for the synthesis of trisubstituted pyrazoles and disubstituted isoxazoles is described. The pyrazole and isoxazole derivatives can be achieved by the reaction of corresponding hydrazones or oximes with phosphine and acid chloride in presence of the base via the in situ trapping of azo-alkene/nitroso-alkene intermediates. The methodology was also capable to provide the diverse heteroaromatics via intramolecular Wittig reaction in diversity-oriented manner that preferentially allows the formation of isoxazole and chromenone-oxime derivatives by altering the reaction conditions. |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | https://esoc2019.abstracts.eu/cTYrcHNyRHNvRkZFbU1qa3BjLzRkM1BUcnBUT0tES09wQ2RaOEY4R1hlTT0=.pdf |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |
