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Author's report Title : Novel Variants in the PRDX 6 Gene and the Risk of Acute Lung Injury Following Major Trauma Version : 1 Date : 22 December 2010
| Content Provider | Semantic Scholar |
|---|---|
| Abstract | Doran and colleagues have performed variant discovery and case-control genetic association analysis of acute lung injury following major trauma with the peroxiredoxin 6 (PRDX6) gene in the manuscript entitled “NOVEL VARIANTS IN THE PRDX6 GENE AND THE RISK OF ACUTE LUNG INJURY FOLLOWING MAJOR TRAUMA”. Although the variation discovery and statistical analysis are quite solid, the primary weakness is no association found between these PRDX6 SNPs studied and ALI. This is a potentially interesting piece of work given the protective role of PRDX6 gene against oxidant injury. |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | https://static-content.springer.com/openpeerreview/art:10.1186%2F1471-2350-12-77/12881_2010_808_ReviewerReport_V1_R3.pdf |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Report |