NDLI: Association Between Khat ( Catha edulis ) Chewing and Infection with Helicobacter pylori : A Case Control Study in Nairobi County

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Association Between Khat ( Catha edulis ) Chewing and Infection with Helicobacter pylori : A Case Control Study in Nairobi County

Content Provider	Semantic Scholar
Author	Hassan, Ma Mohamed, Khalil Zipporah, Ng'ang'a Hudson, Laura
Copyright Year	2015
Abstract	Background : Khat ( Catha edulis ) is a psycho-stimulant substance grown and widely chewed in East Africa. The use of Khat leads to a number of health complications however its adverse effects and prevalence are not well studied. Objective : To compare the prevalence of Khat chewing among H. Pylori infected cases and controls. Design: Individual matched case control study Setting : KEMRI’s Centre for Clinical Research (CCR) and St. Michael’s Digestive Disease and Medical Care. Subjects : Ninety three cases were selected using Rome III criteria for functional dyspepsia, and the controls (n=93) were matched on age and gender. Results : Khat Chewing was associated with infection with H. Pylori . Of the 93 cases, 58.1% were H. Pylori positive with a majority being Khat chewers 67.2% (41/61) and 32.8% (20/61) non-Khat chewers; the two groups were significantly different (p-value=0.007). Functional dyspepsia was associated with H. Pylori. Therefore, participants with functional dyspepsia were twice more likely of being diagnosed with H. Pylori (OR 2.1, 95% CI: 1.2,3.9). Conclusion : The prevalence of H. Pylori infection was found to be higher among khat chewers, indicating that Khat chewing could be a predisposing factor to H. Pylori infection and to gastrointestinal disorders. Community-based awareness creation about the adverse effect of Khat use is thus recommended.
Starting Page	112
Ending Page	119
Page Count	8
File Format	PDF HTM / HTML
DOI	10.4314/eamj.v92i3
Volume Number	92
Alternate Webpage(s)	https://www.ajol.info/index.php/eamj/article/download/121491/110952
Alternate Webpage(s)	https://doi.org/10.4314/eamj.v92i3
Language	English
Access Restriction	Open
Content Type	Text
Resource Type	Article

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