Aut ~ ~ Dio ~ ~ Hic L ~ Alization of Cerebellar Excitatory Amino Acid Binding Sites in the Mouse

Content Provider	Semantic Scholar
Author	Jm, Machinist Lpyt, J. B. P E. N. M. Youn, Aye-Ree
Copyright Year	2002
Abstract	Ahstraet-We have investigated the cellular localization of cerebellar excitatory amino acid binding sites in normal mice, in mice deficient in granule cells and, perhaps, stellate, basket and Golgi cells (granuloprival mice) and in mioe lacking Purkinje cells. in the molecular layer of normal mouse oerebelhun, the q~~~a~-~n~ti~ binding sites were the predominant type of excitatory amino acid reoeptor and there were relatively few ~-me~yl-pupate or ~~t~~~tive binding sites. The granule cell layer of notmal mice contained a mixture of all 3 types, the N-methyl-n-aspartate-sensitive binding sites being predominant. In the molecular layer of granuloprival mice, the number of quisqualate-sensitive binding sites was increased to 214% of control (P
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Alternate Webpage(s)	https://deepblue.lib.umich.edu/bitstream/handle/2027.42/26601/0000142.pdf?sequence=1
Language	English
Access Restriction	Open
Content Type	Text
Resource Type	Article