NDLI: Clinical implications of microRNAs in liver cancer stem cells

Please wait, while we are loading the content...

Clinical implications of microRNAs in liver cancer stem cells

Content Provider	Semantic Scholar
Author	Chai, Stella Hong Yan Ma, Stephanie Spohr
Copyright Year	2013
Abstract	The prognosis of patients diagnosed with hepatocellular carcinoma (HCC) is often dismal, mainly due to late presentation, high recurrence rate, and frequent resistance to chemotherapy and radiotherapy. Accumulating evidence on the differential microRNA (miRNA) expression patterns between non-tumor and HCC tissues or between liver cancer stem cells (CSCs) and non-CSC subsets and the significant clinical implications of these differences suggest that miRNAs are a promising, non-invasive marker for the prognosis and diagnosis of the disease. This perspective article summarizes the current knowledge of miRNAs in liver CSCs and highlights the need for further investigations of the role of miRNAs in regulating liver CSC subsets for possible future clinical applications.
Starting Page	419
Ending Page	426
Page Count	8
File Format	PDF HTM / HTML
Alternate Webpage(s)	http://www.cjcsysu.cn/ENpdf/2013/8/419.pdf
PubMed reference number	23668930v1
Alternate Webpage(s)	https://doi.org/10.5732/cjc.013.10038
DOI	10.5732/cjc.013.10038
Journal	Chinese journal of cancer
Volume Number	32
Language	English
Access Restriction	Open
Subject Keyword	Body tissue Cancer Stem Cells Central Serous Chorioretinopathy Liver and Intrahepatic Biliary Tract Carcinoma Liver carcinoma Liver diseases MicroRNAs Neoplasms Patients
Content Type	Text
Resource Type	Article

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in