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Synthesis and antiulcer activity of 2-[5-substituted-1-H-benzo(d) imidazol-2-yl sulfinyl]methyl-3-substituted quinazoline-4-(3H) ones
| Content Provider | Semantic Scholar |
|---|---|
| Author | Patil, Avinash Ganguly, Swastika Surana, Sanjay Javerilal |
| Copyright Year | 2010 |
| Abstract | Abstract2-[5-substituted-1-H-benzo(d)imidazol-2-yl sulfinyl]methyl-3-substituted quinazoline-4-(3H)-one derivatives were synthesized and tested for antiulcer activity against pylorus ligation-induced, aspirin induced and ethanol induced ulcer in rat model. All the synthesized compounds were characterized by using IR, MS and 1H NMR spectral and elemental analysis. The compounds were scramed for their antiulcer activity: compounds 5k and 5n showed higher activity than omeprazole used as standard. |
| Starting Page | 443 |
| Ending Page | 450 |
| Page Count | 8 |
| File Format | PDF HTM / HTML |
| DOI | 10.1007/s12039-010-0052-5 |
| Volume Number | 122 |
| Alternate Webpage(s) | https://www.ias.ac.in/article/fulltext/jcsc/122/03/0443-0450 |
| Alternate Webpage(s) | https://doi.org/10.1007/s12039-010-0052-5 |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |