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Avaliação preliminar da qualidade da fluoxetina comercializada por farmácias de manipulação em Belo Horizonte/MG
| Content Provider | Semantic Scholar |
|---|---|
| Author | Leal, Alexandre Soares Melo, Fernanda Peixoto Sepe Gomes, Tatiana Cristina Bomfim Santana, Amália Soares Cunha, Luzia Helena Da Saiki, Mitiko |
| Copyright Year | 2017 |
| Abstract | In this study, fourteen samples of fluoxetine being commercialized by thirteen different establishments of the network of magistral pharmacies in the City of Belo Horizonte/MG were assessed. The sampling corresponds to 47,0% of the total 30 different units of preparation of the city, which corresponds to about 180 points of sale. Analyses for determining weight, identification, active ingredient content and uniformity of dosage units were performed by the State Foundation Ezequiel Dias (FUNED /MG) based on methodologies described by reference pharmacopoeias. Irregularities, on the labeling and the content testing, were observed in some samples. It was also investigated, through the technique of neutron activation analysis (NAA), the presence and concentrations of metals and other inorganic impurities. The results showed the presence of elements such as As, Br, Cr Co, Cr, Hf and others, that even at low concentrations, may be harmful to human health if consumed steadily for a long term. |
| Starting Page | 76 |
| Ending Page | 83 |
| Page Count | 8 |
| File Format | PDF HTM / HTML |
| DOI | 10.22239/2317-269x.00810 |
| Volume Number | 5 |
| Alternate Webpage(s) | https://visaemdebate.incqs.fiocruz.br/index.php/visaemdebate/article/download/810/359 |
| Alternate Webpage(s) | https://doi.org/10.22239/2317-269x.00810 |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |
