Epidemiological and microbiological analysis of ventilator-associated pneumonia patients in a public teaching hospital.

Content Provider	Semantic Scholar
Author	Silva, João Manoel Da Rezende, Ederlon Alves De Carvalho Guimarães, Thaís Campos, Edvaldo V. Dos Magno, Luiz André Consorti, Lívia Pereira, Renata Andréa Pietro Nascimento, Maria De Lourdes Mendonça, João Silva De
Copyright Year	2007
Abstract	Ventilator-associated pneumonia (VAP) is the most commonly-acquired infection in patients in intensive care units. We analyzed epidemiological and microbiological characteristics and the outcome, in a cohort of critically-ill patients with confirmed diagnosis of VAP. All patients who had been on mechanical ventilation (MV) for more than 48 hours were included in our study; material collection for microbiological analysis was done within the first 24 hours after beginning treatment or after changing antibiotics. There were 55/265 (20.7%) VAP cases diagnosed, at a rate of 21.6 episodes per 1,000 days of mechanical ventilation. Mean age of the patients was 66 years, with a mean APACHE II score of 26.7 + 7.0; male patients were more prevalent. The mortality rates in the intensive care unit (ICU) and during the hospital stay were 71% and 80%, respectively. MV duration in patients with VAP was 17 (range 3-43) days and among patients who had not developed VAP, 6 (2-32) days (p < 0.0001). 98.2% of the samples were positive, with a high prevalence of Gram-negative bacteria, mainly Acinetobacter calcoaceticus. Risk factors for death included age, MV duration and surgery. VAP incidence in this sample of critically-ill patients was high, with a high mortality rate. Control and prevention strategies based on continuing education of healthcare workers, developed by a multidisciplinary team, should be encouraged to minimize morbimortality of this infection.
File Format	PDF HTM / HTML
Alternate Webpage(s)	http://www.scielo.br/pdf/bjid/v11n5/a09v11n5.pdf
PubMed reference number	17962875v1
Volume Number	11
Issue Number	5
Journal	The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases
Language	English
Access Restriction	Open
Subject Keyword	APACHE II Academic Medical Centers Cessation of life Critical Illness Education, Continuing Eighty Epidemiology Gram-Negative Bacteria Infection Mechanical ventilation Microbiological Mortality Vital Statistics Patients Pneumonia Pneumonia, Ventilator-Associated Respiration Ventilator - respiratory equipment gram intensive care unit
Content Type	Text
Resource Type	Article