Inner ear autoantibodies in patients with sensorineural hearing loss.

Content Provider	Semantic Scholar
Author	Kosaka, Kazuki Yamanobe, Susumu Tomiyama, Shunichi Yagi, Toshiaki
Copyright Year	1995
Abstract	In order to identify the inner ear autoantibodies, sera of 195 patients with sensorineural hearing loss and/or vertigo were reached with bovine inner ear antigen by western blotting method. Positive reaction was seen at several molecular weights, in which 33-35 kD, 42 kD and 68 kD were highly reactive. In moderate to severe hearing loss patients, positive reactions with 33-35 kD, 42 kD, 68 kD and others were 25.8%, 26.8%, 26.8% and 71.5% respectively. On the other hand, a positive rate did not clearly correlate with diagnostic entities. Further study to purify inner ear antigen may evaluate inner ear autoimmune disease.
Starting Page	43
Ending Page	50
Page Count	8
File Format	PDF HTM / HTML
Alternate Webpage(s)	https://www.jstage.jst.go.jp/article/jser1971/52/Suppl-9/52_Suppl-9_51/_pdf
PubMed reference number	7610860v1
Volume Number	519
Journal	Acta oto-laryngologica. Supplementum
Language	English
Access Restriction	Open
Subject Keyword	Autoimmune Diseases Cattle Ear Diseases Labyrinth Molecular Weight Patients Sensorineural Hearing Loss (disorder) Vertigo Western Blotting hearing impairment
Content Type	Text
Resource Type	Article