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Direct UV photocrosslinking of poly ( N-vinyl-2-pyrrolidone ) ( PVP ) to produce hydrogels
| Content Provider | Semantic Scholar |
|---|---|
| Copyright Year | 2003 |
| Abstract | Hydrogels for biomedical purposes, made from synthetic polymers as starting materials and free of co-adjuvant molecules, have been produced almost exclusively by high-energy radiative processes. On the other hand, UV photocrosslinking of such materials has been used in conjunction of monomers and/or photoinitiators. This work was addressed to the analysis of poly(N-vinyl-2-pyrrolidone) (PVP) submitted to direct photocrosslinking in aqueous solution, using low pressure Hg lamp (lem 1⁄4 254 nm). The process efficiency was evaluated, and the properties of the hydrogel formed were determined. The product thus formed has similar microand macroscopic properties, as compared to hydrogels produced by high-energy radiation and presents no cytotoxicity. These results demonstrated the viability of using this method as a versatile alternative to hydrogel production, broadening the possibility of its production where high-energy radiation facilities are not available. q 2003 Published by Elsevier Ltd. |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | http://www2.iq.usp.br/docente/lhc/lab/polymer_UV_hydrogels_lilian.pdf |
| Language | English |
| Access Restriction | Open |
| Subject Keyword | Drug Delivery Systems Hydrogel Hydrogels Mercury PQCC Pharmaceutical Adjuvants Poly A Poly Adenosine Diphosphate Ribose Povidone Protected Media Path Scientific Publication Synthetic Polymer Synthetic intelligence UV mapping monomer |
| Content Type | Text |
| Resource Type | Article |