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Construction of 1,3-disubstituted 4-oxo-1,4-dihydroquinolines as a potential antibacterial agents
| Content Provider | Semantic Scholar |
|---|---|
| Author | El-Essawy, Farag A. G. Boshta, Nader M. Alotaibi, Mshari A. Elsayed, Mohamed Sabry Abd Elraheam Tarabees, Reda Saleh, Ebtsam A. |
| Copyright Year | 2016 |
| Abstract | A novel series of 1,3-disubstituted 4-oxo-1,4-dihydroquinolines as antimicrobial agents were designed and synthesized. Their structures have been confirmed using spectroscopic analyses (IR, NMR, and EI-MS). Most of the newly prepared compounds were screened for their antimicrobial activities against two Gram-positive bacterial strains and six Gram-negative bacterial strains. Many of the synthesized compounds displayed a high antimicrobial activity in comparison with reference drugs, for example compounds 4–6, 15, 17, and 18. |
| Starting Page | 8157 |
| Ending Page | 8174 |
| Page Count | 18 |
| File Format | PDF HTM / HTML |
| DOI | 10.1007/s11164-016-2586-8 |
| Volume Number | 42 |
| Alternate Webpage(s) | http://staff.usc.edu.eg/uploads/3d1b0a9742de5a67099e5b410109b436.pdf |
| Alternate Webpage(s) | https://doi.org/10.1007/s11164-016-2586-8 |
| Journal | Research on Chemical Intermediates |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |
