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Energy Transfer Highway in Nd3+-Sensitized Nanoparticles for Efficient near-Infrared Bioimaging.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Cao, Cong Xue, Meng Zhu, Xingjun Yang, Pengyuan Feng, Weisong Li, Fuyou |
| Copyright Year | 2017 |
| Abstract | Despite the large absorption cross-section of Nd3+ dopant as a sensitizer in lanthanide doped luminescence system, the strong cross-relaxation effect of it impedes the promotion of doping concentration and thus reduces the utilization of excitation light. In this work, we introduce a highly efficient acceptor, Yb3+ ion, which can quickly receive energy from Nd3+ ions, to construct an energy transfer highway for the enhancement of near-infrared emission. By using the energy transfer highway, the doping amount of Nd3+ ions in our NaYF4:Yb,Nd@CaF2 core/shell nanoparticles (CSNPs) can be markedly elevated to 60%. The quantum yield of CSNPs was determined to be 20.7%, which provides strong near-infrared luminescence for further bioimaging application. Remarkably, deep tissue penetration depth (∼10 mm) in in vitro imaging and high spatial resolution of blood vessel (∼0.19 mm) in in vivo imaging were detected clearly with weak autofluorescence, demonstrating that probes can be used as excellent NIR biosensors. |
| Starting Page | 18540 |
| Ending Page | 18548 |
| Page Count | 9 |
| File Format | PDF HTM / HTML |
| DOI | 10.1021/acsami.7b04305 |
| PubMed reference number | 28492075 |
| Journal | Medline |
| Volume Number | 9 |
| Issue Number | 22 |
| Alternate Webpage(s) | http://www.meplab.fudan.edu.cn/d/file/infonet/assays/2018-06-23/5564f56551e39ef76c13c486e5e7419d.pdf |
| Alternate Webpage(s) | https://doi.org/10.1021/acsami.7b04305 |
| Journal | ACS applied materials & interfaces |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |
