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Do commonly used ventilator settings for mechanically ventilated adults have the potential to embed secretions or promote clearance?
| Content Provider | Semantic Scholar |
|---|---|
| Author | Ntoumenopoulos, George Shannon, Harriet |
| Copyright Year | 2011 |
| Abstract | BACKGROUND Intubation and mechanical ventilation can impair mucociliary clearance and cause secretion retention, airway occlusion, atelectasis, and pneumonia. Animal and laboratory work has demonstrated that mechanical ventilator settings can generate a flow bias (inspiratory or expiratory) that may result in mucus movement either away from the ventilator (deeper into the lungs) or toward the ventilator (toward the mouth), respectively. An absolute difference of 17 L/min, and a relative difference of ≥ 10%, between the expiratory and inspiratory flow have been reported as thresholds for mucus movement. METHODS We measured baseline peak inspiratory and expiratory flows during quiet mechanical ventilation in a convenience sample of 20 intubated and ventilated adult patients. RESULTS Nineteen patients had an inspiratory flow bias of ≥ 10%. Eight patients had an absolute mean inspiratory flow bias of ≥ 17 L/min. CONCLUSIONS Commonly used mechanical ventilator settings generate an inspiratory flow bias that may promote secretion retention. |
| Starting Page | 63 |
| Ending Page | 70 |
| Page Count | 8 |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | http://rc.rcjournal.com/content/respcare/56/12/1887.full.pdf |
| PubMed reference number | 21682986v1 |
| Alternate Webpage(s) | https://doi.org/10.4187/respcare.01229 |
| DOI | 10.4187/respcare.01229 |
| Journal | Respiratory care |
| Volume Number | 56 |
| Issue Number | 12 |
| Language | English |
| Access Restriction | Open |
| Subject Keyword | Airway Obstruction Atelectasis Bodily secretions Bronchoscopy Convenience Sampling Expiration, function Flow Inappropriate ADH Syndrome Inspiration function Lung Mechanical Ventilator Mechanical ventilation Mucociliary Clearance Patients Physical therapy Pneumonia Respiration Ventilator - respiratory equipment peak expiratory flow (procedure) |
| Content Type | Text |
| Resource Type | Article |
