Edetic Acid [Ethylenediamine Tetraacetic Acid, Edta]

Content Provider	Semantic Scholar
Author	Belal, Fathalla Al-Badr, Abdullah A.
Copyright Year	2002
Abstract	Publisher Summary This chapter focuses on the drug edetic acid. Edetic acid is obtained as crystals from water; the acid is the form most potent in removing metals from solutions. It may be added to drawn blood to prevent clotting and is used in pharmaceutical analysis and for the removal or inactivation of unwanted ions in solution. Ethylenediamine tetraacetic acid (EDTA) is most effective in preventing the oxidation of thiol group in drugs, such as captopnl. The edetate calcium disodium salt is primarily used in the diagnosis and treatment of lead poisoning. The chapter presents various methods of preparation of this drug as well as various method of analysis of this drug such as compendial tests, electrochemical analysis, spectroscopic analysis, and chromatographic methods of analysis. It discusses its physical properties such as ionization constants, solubility characteristics, and partition coefficient. The chapter concludes with a discussion on its biological properties such as activity, toxicity, and safety.
Starting Page	57
Ending Page	104
Page Count	48
File Format	PDF HTM / HTML
DOI	10.1016/S1075-6280(02)29004-7
Volume Number	29
Alternate Webpage(s)	http://faculty.ksu.edu.sa/Al-Badr/Documents/%D9%8DAl-Badr%20SD%20links.pdf
Alternate Webpage(s)	https://doi.org/10.1016/S1075-6280%2802%2929004-7
Language	English
Access Restriction	Open
Content Type	Text
Resource Type	Article