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Pulmonary vein isolation and left atrial complex-fractionated atrial electrograms ablation for persistent atrial fibrillation with phased radio frequency energy and multi-electrode catheters: efficacy and safety during 12 months follow-up.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Mulder, Anton A. W. Wijffels, Maurits Wever, Eric F. D. Boersma, Lucas V. A. |
| Copyright Year | 2011 |
| Abstract | AIMS Ablation for persistent atrial fibrillation (AF) remains a difficult and time-consuming procedure with varying degrees of success. We evaluated the long-term effects of a novel approach for ablation of persistent AF using multi-electrode catheters. METHODS AND RESULTS In 89 patients with longstanding persistent AF (>1 year), multi-electrode ablation was performed with a pulmonary vein ablation catheter (PVAC), a multi-array septal catheter (MASC), and a multi-array ablation catheter (MAAC) for ablation of complex-fractionated atrial electrograms (CFAE) at the septum, left atrial (LA) roof, floor, posterior wall, and mitral isthmus. Follow-up was performed at 6 and 12 months with electrocardiogram, 7 days Holter, and occasionally ambulant event recordings. Average procedure and fluoroscopy times were 112 ± 32 and 21 ± 10 min. The pre-specified endpoint of pulmonary vein isolation and LA CFAE ablation was reached in all patients. No procedural complications were observed. At 12 months after a single treatment 44 of 89 (49%) remained in sinus rhythm, including direct current cardioversion in 12 patients. At 12 months, after a redo PVAC/MASC/MAAC, an additional 6 of 15 patients (40%) were free of AF. In 18 of 89 (20%) patients AF was changed to paroxysmal. CONCLUSIONS In this single centre study, ablation for longstanding persistent AF with the PVAC/MASC/MAAC resulted in 56% freedom of AF at 1 year after 1.2 ± 0.4 procedures. This approach is time efficient and has a favourable safety profile. |
| File Format | PDF HTM / HTML |
| DOI | 10.1093/europace/eur204 |
| PubMed reference number | 21750096 |
| Journal | Medline |
| Volume Number | 13 |
| Issue Number | 12 |
| Alternate Webpage(s) | https://watermark.silverchair.com/eur204.pdf?token=AQECAHi208BE49Ooan9kkhW_Ercy7Dm3ZL_9Cf3qfKAc485ysgAAAk4wggJKBgkqhkiG9w0BBwagggI7MIICNwIBADCCAjAGCSqGSIb3DQEHATAeBglghkgBZQMEAS4wEQQM-_YqHL_F-1Z4YsZSAgEQgIICAStCpM8iMYEZayczm6OANy_I_ZkF7o6k31AmWae5HtR74COavzc3R8VhJDppB01IwIynB-ZlgLTn8dGPh1Fj00CL1ZZzmYbUMheqiByNKgb4Cz9S1Fa2CxuOGp_1iwiUfcUMyKvVNEQcXiaWsL-HofhAZbb8tXWmckYjrdzzH4w4CZnjrqfCEDpR2mME6yljPnMuIkvR3jqKi9MXMJJEt6oHRBbe3YB9X-q4wqMJsYH6V1M-ETgSyhMVusZaOLDbQ2cjh9TMYQSFThh_9Jz8WzBI2NnSP4q0fbTtjdyRkJraAw2nSdc2t_wCbWISoApsN0ysKwkRDC_Lj8H6X8PQ6CMxPJqZWmpkyez80s6BgSmJ95LGZEVrpViqqyc6QhLuBYsZoOkmEv1IudGgA1ZLfvXkqY2E_RbBu9B-vAvlwT_Gsuq_00IBL5wv36kb5s1zeUySY--3y1CRnlA-EDROXmHkE80CFTPEH-EemZchahV83LjuiaYZ0X45a6HCGHpEs7bbBdJRqBM79aH2TCiXzdbH7EbXjlHC6j1PRba3kkEwxVoJPg1G7QONfIqQ6okwzWAOFjAMRIKl5nO2_E6IWa21RAZsY51sLuPO178e4Cc-JEzg2HgYlDQt9euWxssP9tSbQNy-eqFO9f1c6bGJcPRhSU_9OJBzeu_DCKgX1rpQGA |
| Alternate Webpage(s) | https://doi.org/10.1093/europace%2Feur204 |
| Journal | Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |
