Kolesterol merupakan unsur penting dalam tubuh yang diperlukan untuk mengatur proses kimiawi di dalam tubuh, tetapi kolesterol dalam jumlah tinggi bisa menyebabkan terjadinya aterosklerosis yang akhirnya akan berdampak pada penyakit jantung koroner (Rahayu, 2005). Freeman & Junge (2005) mengatakan b

Content Provider	Semantic Scholar
Author	Persea, Biji Alpukat Rahman, Nurdin Ratman, Dan
Copyright Year	2018
Abstract	Cholesterol is an important element in the body needed to regulate chemical processes in the body, but high amounts of cholesterol can lead to atherosclerosis which ultimately will have an impact on coronary heart disease. This study aims to knowing phytochemicals contained in an avocado (persea americana mill) seeds’ extract and determine the concentration of the avocado (persea americana mill) seeds’ extract can lower mice’s blood (mus musculus) hypercholesterol levels in optimum. The animals tested were male mice which totaled 15 mice induced by propylthiouracil and high-fat feed. The mice were divided into 5 groups with different treatment. Treatment I, II, and III were given avocado seeds’ extract with a concentration of 10%, 20% and 40% respectively, treatment IV was given simvastatin as positive control, and treatment V was given standard food and aquades as negative control. The data gained was analyzed through analysis of variance (ANOVA) statistical test which was followed by Duncan’ stest. The research findings show that avocado seeds’ extract is considered as positive to contain flavonoids, saponins, and tannins. The concentration of the avocado seeds’ extract which lowers blood hypercholesterol levels in optimum way is 10% (b/v).
File Format	PDF HTM / HTML
Alternate Webpage(s)	http://jurnal.untad.ac.id/jurnal/index.php/JAK/article/download/9444/7504
Language	English
Access Restriction	Open
Content Type	Text
Resource Type	Article