Contrast Sensitivity versus Visual Evoked Potentials in Multiple Sclerosis

Content Provider	Semantic Scholar
Author	Shandiz, Javad Heravian Nourian, Abbas Hossaini, Mercedeh Bahr Moghaddam, Hadi Ostadi Yekta, Abbasali Sharifzadeh, Laleh Marouzi, Parviz
Copyright Year	2010
Abstract	PURPOSE To compare the Cambridge contrast sensitivity (CS) test and visual evoked potentials (VEP) in detecting visual impairment in a population of visually symptomatic and asymptomatic patients affected by clinically definite multiple sclerosis (MS). METHODS Fifty patients (100 eyes) presenting with MS and 25 healthy subjects (50 eyes) with normal corrected visual acuity were included in this study. CS was determined using the Cambridge Low Contrast Grating test and VEP was obtained in all eyes. Findings were evaluated in two age strata of 10-29 and 30-49 years. RESULTS Of the 42 eyes in the 10-29 year age group, CS was abnormal in 22 (52%), VEP was also abnormal in 22 (52%), but only 12 eyes (28%) had visual symptoms. Of the 58 eyes in the 30-49 year group, CS was abnormal in 7 (12%), VEP was abnormal in 34 (58%), while only 11 eyes were symptomatic. No single test could detect all of the abnormal eyes. CONCLUSION The Cambridge Low Contrast Grating test is useful for detection of clinical and subclinical visual dysfunction especially in young patients with multiple sclerosis. Nevertheless, only a combination of CS and VEP tests can detect most cases of visual dysfunction associated with MS.
Starting Page	175
Ending Page	181
Page Count	7
File Format	PDF HTM / HTML
PubMed reference number	22737353
Journal	Medline
Volume Number	5
Alternate Webpage(s)	http://www.sid.ir/en/VEWSSID/J_pdf/118320100307.pdf
Journal	Journal of ophthalmic & vision research
Language	English
Access Restriction	Open
Content Type	Text
Resource Type	Article