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Prevalence and prognosis of congestive heart failure in Saudi patients admitted with acute coronary syndrome (from SPACE registry).
| Content Provider | Semantic Scholar |
|---|---|
| Author | Albackr, Hanan B. Alhabib, Khalid F. Ullah, Anhar A. Alfaleh, Hussam F. Hersi, Ahmad Alshaer, Fayez Alnemer, Khalid A. Saif, Shukri Al Taraben, Amir N. Kashour, Tarek |
| Copyright Year | 2013 |
| Abstract | OBJECTIVES The aim of this study was to assess the prevalence, clinical features, and in-hospital outcomes of heart failure in patients with acute coronary syndrome (ACS). MATERIALS AND METHODS The Saudi Project for Assessment of Coronary Events recruited patients admitted with ACS from 17 hospitals in Saudi Arabia from 2005 to 2007. The outcomes of ACS patients with congestive heart failure (CHF) compared with those without CHF were analyzed. RESULTS A total of 4523 patients with ACS were identified, of whom 905 (20%) had CHF. Compared with no CHF, patients with CHF were older (62±13.1 vs. 57±12.9 years; P=0.001), less likely to be men (70 vs. 79%; P=0.001), likely to present with non-ST-segment elevation myocardial infarction (48 vs. 36%; P=0.001), likely to have diabetes (71 vs. 54%; P=0.001), hypertension (64 vs. 54%; P=0.001) and previous history of coronary artery disease (53 vs. 43%; P=0.001), and likely to have significant left ventricular systolic dysfunction (left ventricular ejection fraction <35%) (56 vs. 30%; P=0.001). Patients with CHF were less likely to receive in-hospital β-blockers (74 vs. 86%; P=0.001) and a percutaneous coronary intervention (19 vs. 50%; P=0.001). Adjusted in-hospital mortality and cardiogenic shock were higher in the CHF group (odds ratio 4.43, 95% confidence interval 2.52-7.78; and odds ratio 3.51, 95% confidence interval 2.23-5.52), respectively. CONCLUSION ACS patients with CHF in the Saudi Project for Assessment of Coronary Events were older, more likely to have more cardiac risk factors, and less likely to be treated with optimum medical treatment on admission. These findings were associated with higher incidence of their in-hospital adverse outcomes. More aggressive treatment is warranted to improve prognosis. |
| Starting Page | 596 |
| Ending Page | 601 |
| Page Count | 6 |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | http://faculty.ksu.edu.sa/14402/publications/mca11568%20space%20hf.pdf |
| Alternate Webpage(s) | http://www.sha-conferences.com/files/presentation2011/day3/082006.pdf |
| PubMed reference number | 23928809v1 |
| Alternate Webpage(s) | https://doi.org/10.1097/MCA.0b013e328364d98f |
| DOI | 10.1097/mca.0b013e328364d98f |
| Journal | Coronary artery disease |
| Volume Number | 24 |
| Issue Number | 7 |
| Language | English |
| Access Restriction | Open |
| Subject Keyword | Acute Coronary Syndrome Arteriopathic disease Confidence Intervals Congestive heart failure Coronary Artery Disease Diabetes Mellitus Ejection fraction (procedure) Forecast of outcome Hospital admission Hypertensive disease Left ventricular ejection fraction Left ventricular systolic dysfunction Myocardial Infarction Odds Ratio Patients Percutaneous Coronary Intervention Premature ventricular contractions Registries Shock, Cardiogenic Ventricular Dysfunction, Left |
| Content Type | Text |
| Resource Type | Article |