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NEMA NU 4-2008 Performance Evaluation of Albira : A Two-Ring Small-Animal PET System Using Continuous LYSO Crystals
| Content Provider | Semantic Scholar |
|---|---|
| Author | Volgyes, David McKeown, Clare Waldeck, Jens Anderson, Kurt I. |
| Copyright Year | 2016 |
| Abstract | Goals: This paper presents the performance review based on a dual-ring Positron Emission Tomography (PET) scanner being a part of Bruker Albira: a multi-modal small-animal imaging platform. Each ring of Albira PET contains eight detectors arranged as octagon, and each detector is built using a single continuous lutetium-yttrium oxyorthosilicate crystal and multi-anode photo multiplier tube. In two-ring configuration, the scanner covers 94.4 mm in axialand 80 ́80 mm in trans-axial direction, which is sufficient to acquire images of small animals (e.g. mice) without the need of moving the animal bed during the scan. Methods: All measurements and majority of data processing were performed according to the NEMA NU4-2008 standard with one exception. Due to the scanner geometry, the spatial resolution test was reconstructed using iterative algorithm instead of the analytical one. The main performance characteristics were compared with those of the other PET sub-systems of tri-modal smallanimal scanners. Results: The measured spatial resolution at the centre of the axial field of view in radial, tangential and axial directions was 1.72, 1.70 and 2.45 mm, respectively. The scatter fraction for the mouse-like phantom was 9.8% and for the rat-like phantom, 21.8%. The maximum absolute sensitivity was 5.30%. Finally, the recovery co-efficients for 5, 4, 3, 2, 1 mm diameter rods in image quality phantom were: 0.90, 0.77, 0.66, 0.30 and 0.05, respectively. Conclusion: The Bruker Albira is a versatile small-animal multi-modal device that can be used for variety of studies. Overall the PET sub-system provides a good spatial resolution coupled with better-than average sensitivity and the ability to produce good quality animal images when administering low activities. |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | http://benthamopen.com/contents/pdf/MEDJ/MEDJ-3-12.pdf |
| Alternate Webpage(s) | https://benthamopen.com/contents/pdf/MEDJ/MEDJ-3-12.pdf |
| Language | English |
| Access Restriction | Open |
| Subject Keyword | Administration procedure CT scan Detectors Diameter (qualifier value) Dual Image quality Imaging phantom Iterative method Marichromatium sp. Nu4 Modal logic NEMA (machine) Numerous Performance Evaluation Phantom reference Phantoms, Imaging Photomultiplier Polyethylene terephthalate Positron-Emission Tomography Positrons Preclinical imaging Radial (radio) Rod Photoreceptors Scanner Device Component Source-to-source compiler Tomography, Emission-Computed Triangular function Trimipramine Yttrium algorithm motexafin lutetium |
| Content Type | Text |
| Resource Type | Article |
