Enfrentando el bioterrorismo: aspectos epidemiológicos, clínicos y preventivos de la viruela

Content Provider	Semantic Scholar
Author	Franco-Paredes, Carlos Río, Carlos Del Nava-Frías, Margarita Rangel-Frausto, Sigfrido Téllez, Ildefonso Santos-Preciado, José Ignacio
Copyright Year	2003
Abstract	The worldwide eradication of smallpox, a major achievement in public health, is currently threatened by the risk of bioterrorism. The debate on the destruction of the Variola virus in the two reference laboratories of the World Health Organization has dramatically switched to the preservation of the remaining virus after the September 2001 terrorist events in the U.S. along with the intentional release of Bacillus anthracis in the U.S. The risk of intentional release of Variola virus constitutes a minimal, yet possible risk. A smallpox epidemic could have a devastating impact due to its elevated morbidity and mortality that would inflict in nonimmune human population, in addition to the ensuing panic and social unrest. Therefore, the development of national preparedness and response plans along with the availability of smallpox vaccine to be used in the post-exposure phase represent a fundamental part of the preventive efforts to cope with bioterrorism. Reestablishing a preventive vaccination program was recently recommended by the Advisory Committee on Immunization Practices (ACIP). However, the vaccine currently available has historically been associated with serious adverse reactions, even death. Thus, this recommendation has not been universally accepted. To counter an epidemic of smallpox, medical personnel in the frontline need to be prepared with updated smallpox infor
Starting Page	298
Ending Page	309
Page Count	12
File Format	PDF HTM / HTML
DOI	10.1590/S0036-36342003000400009
Alternate Webpage(s)	http://www.scielosp.org/pdf/spm/v45n4/a09v45n4.pdf
Alternate Webpage(s)	https://doi.org/10.1590/S0036-36342003000400009
Volume Number	45
Language	English
Access Restriction	Open
Content Type	Text
Resource Type	Article