NDLI: Clinical Features of Brain Abscesses in Neonates and Children: A Single Center Experience from 1997 to 2006

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Clinical Features of Brain Abscesses in Neonates and Children: A Single Center Experience from 1997 to 2006

Content Provider	Semantic Scholar
Author	Lee, Teak Jin Chun, Jin-Kyong Kim, Ki Hwan Kim, Dong Soo
Copyright Year	2008
Abstract	Purpose :We evaluated clinical presentations of brain abscesses, including predisposing factors, causative organisms, and mortality rate in neonates and children. Methods :We retrospectively reviewed the medical charts of neonates and children with brain abscesses treated at Severance Hospital from January 1997 through December 2006. Results : Among 27 neonates and children with brain abscesses, overall mortality was 22 % and 38% of survivors developed neurologic sequelae. The mortality rate was 38% in 8 infants with brain abscesses. The most common location of brain abscesses were frontal and parietal lobes, followed by temporal lobe. There were 7 cases with multiple brain abscesses. Streptococci (33%), Staphylococci (27%), and Gram-negative enterics (20%) were commonly isolated. The common predisposing conditions were neurosurgical procedure (30 %), cyanotic congenital heart disease (15%), and sinusitis/otitis (7%). Fever (74%), headache (37%), nausea/vomiting (33%), and altered mental status (33%) occurred commonly. Compared with children older than 1 year of age, infants were associated with multiple brain abscesses (63%, P=0.011) and high rates of death or neurologic sequelae (88%, P= 0.033). Conclusion :We should have a high index of suspicion in order to recognize the condition as early as possible, especially in infancy with brain abscesses who presents vague or nonspecific symptoms and signs. (Korean J Pediatr Infect Dis 2008;15:29-34)
Starting Page	29
Ending Page	29
Page Count	1
File Format	PDF HTM / HTML
DOI	10.14776/kjpid.2008.15.1.29
Volume Number	15
Alternate Webpage(s)	https://ir.ymlib.yonsei.ac.kr/bitstream/22282913/107254/1/T200800987.pdf
Alternate Webpage(s)	https://doi.org/10.14776/kjpid.2008.15.1.29
Language	English
Access Restriction	Open
Content Type	Text
Resource Type	Article

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