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Cobalt-catalyzed oxidative [3 + 2] cycloaddition reactions: an efficient synthesis of pyrrolo- and imidazo-[2,1-a]isoquinolines.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Feng, Chengtao Su, Jihu Yan, Yizhe Guo, Fengfeng Wang, Zhiyong |
| Copyright Year | 2013 |
| Abstract | A cobalt-catalyzed oxidative [3 + 2] cycloaddition cascades of dihydroisoquinoline esters with nitroolefins or N-sulfuryl aldimines were developed at room temperature. A multi-component reaction for the synthesis of 5,6-dihydroimidazo[2,1-a]isoquinolines were also realized under almost identical conditions. This method is particularly suitable for the synthesis of tricyclic nitrogen heterocycles due to its simple manipulation, wide scope of the reaction substrates and excellent regioselectivity. |
| File Format | PDF HTM / HTML |
| DOI | 10.1039/c3ob41424h |
| PubMed reference number | 23995231 |
| Journal | Medline |
| Volume Number | 11 |
| Issue Number | 39 |
| Alternate Webpage(s) | http://www.rsc.org/suppdata/ob/c3/c3ob41424h/c3ob41424h.pdf |
| Alternate Webpage(s) | https://doi.org/10.1039/c3ob41424h |
| Journal | Organic & biomolecular chemistry |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |