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Non-invasive detection of liver fibrosis with transient elastography and serum markers
| Content Provider | Semantic Scholar |
|---|---|
| Author | Castéra, Laurent Lévêque, Haut |
| Copyright Year | 2010 |
| Abstract | Key messages: 1. Currently available methods for the non invasive assessment of liver fibrosis include transient elastography and serum markers. 2. Two aims are clinically relevant: 1) detection of significant fibrosis (indication for antiviral treatment in chronic viral hepatitis); 2) detection of cirrhosis (indication for screening of oesophageal varices and hepatocellular carcinoma). 3. Transient elastography and serum markers of fibrosis have been mostly studied and validated in chronic hepatitis C with similar performance for the diagnosis of significant fibrosis but remain to be validated in other chronic liver diseases. 4. The combination of two unrelated methods such as transient elastography and serum markers could increase the diagnostic accuracy, particularly for the diagnosis of significant fibrosis in hepatitis C but deserves to be evaluated in other chronic liver diseases. 5. Transient elastography currently appears as the most accurate tool for early detection of cirrhosis and may have prognostic value in this setting. However, it cannot replace so far upper GI endoscopy for screening of oesophageal varices in patients with cirrhosis. |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | http://cds.ismrm.org/protected/10MProceedings/files/Tues%20C05_01%20Castera.pdf |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |