Loading...
Please wait, while we are loading the content...
Similar Documents
Responses of serum lipoproteins to dietary cholesterol and type of fat in the baboon.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Mcmahan, Clyde |
| Copyright Year | 1981 |
| Abstract | We examined the effects of dietary cholesterol (less than 0.01 and 1.7 mg/Kcal) and type of fat (saturated, coconut oil; polysaturated, corn oil) on very low density plus low density lipoprotein (VLDL + LDL) and high density lipoprotein (HDL) cholesterol in 24 young baboons (12 male, 12 female) Paplo sp.) in a crossover design experiment. The oils contributed 40% of calories. Total serum cholesterol concentration on the low cholesterol-polyunsaturated fat diet averaged 120 mg/dl; on the high cholesterol-saturated fat diet, 245 mg/dl; and on the other two cholesterol-fat diet combinations, about 200 mg/dl. There was a significant interaction between cholesterol and type of fat in their effects on VLDL + LDL cholesterol, but not in their effects on HDL cholesterol. Dietary cholesterol elevated VLDL + LDL cholesterol when fed with both types of fat, but elevated it more when fed with polyunsaturated fat than with saturated fat. Saturated fat elevated VLDL + LDL cholesterol when dietary cholesterol was low, but not when dietary cholesterol was high. Saturated fat consistently elevated HDL cholesterol more than did dietary cholesterol. The response of apolipoprotein B concentrations to dietary components was similar to that of VLDL + LDL cholesterol. These results indicate that dietary cholesterol and type of fat have different effects on the distribution of cholesterol among the major serum lipoproteins of the baboon. |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | http://atvb.ahajournals.org/content/atvbaha/1/5/337.full.pdf |
| Alternate Webpage(s) | http://atvb.ahajournals.org/content/atvbaha/1/5/337.full.pdf?download=true |
| PubMed reference number | 6956267v1 |
| Volume Number | 1 |
| Issue Number | 5 |
| Journal | Arteriosclerosis |
| Language | English |
| Access Restriction | Open |
| Subject Keyword | Apolipoproteins B Cholesterol Coconut Oil Corn Oil Diet, High-Fat Fat embolism (disorder) Fatty acid glycerol esters High Density Lipoproteins Low-Density Lipoproteins Nutrition, Calories Papio Platelet Glycoprotein 4, human Saturated fat Very low density lipoprotein kilocalorie mg/dl |
| Content Type | Text |
| Resource Type | Article |