Antibacterial and biological properties of silver-loaded coralline hydroxyapatite

Content Provider	Semantic Scholar
Author	Zhang, Yu Yin, Qing-Shui Zhao, Hua-Fu Li, Jian Wei, Yue-Teng Cui, Fuzhai Huang, Huayang
Copyright Year	2010
Abstract	The antibacterial and biological properties of silver-loated coralline hydroxyapatite (Ag-CHA) as a new antibacterial implant material were investigated in this study. Compared to other antibiotic and chemical bactericidal agents, Ag+ does not bring bacterial resistance to drugs and has less toxicity. The porous CHA was formed by hydrothermal exchange, then Ag+ was loated onto CHA through ion exchange and adsorption. The microstructure and composition of Ag-CHA were characterized by scanning electron microscopy (SEM), Rutherford backscattering spectrometry (RBS), and energy dispersive spectrometry (EDS). Antibacterial activity of Ag-CHA on the clinical strains of Escherichia coli (E. Coli) and Staphylococcus aureus (S. Aureus) was evaluated by the flat plate diffusion method. The antibacterial activity of Ag-CHA was found to be correlated with the concentration of Ag+ in a dose-dependent manner, which indicated that the optimal antibacterial and biocompatible effects of Ag-CHA could be obtained with Ag+ concentrations from 5×10−5 to 1×10−4 mol/L.
Starting Page	359
Ending Page	365
Page Count	7
File Format	PDF HTM / HTML
DOI	10.1007/s11706-010-0112-2
Alternate Webpage(s)	https://page-one.springer.com/pdf/preview/10.1007/s11706-010-0112-2
Alternate Webpage(s)	https://doi.org/10.1007/s11706-010-0112-2
Volume Number	4
Language	English
Access Restriction	Open
Content Type	Text
Resource Type	Article