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Asymmetric Michael addition reactions of nitroalkanes to 2-furanones catalyzed by bifunctional thiourea catalysts.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Bai, Zhushuang Ji, Ling Ge, Zemei Wang, Xiaoming Li, Runtao |
| Copyright Year | 2015 |
| Abstract | The first bifunctional thiourea catalyzed asymmetric Michael addition reactions of nitroalkanes to 2-furanones are described. The highly functionalized γ-lactones with two or three consecutive stereogenic carbons were obtained in high yields (up to 99%), high diastereoselectivities (up to >20 : 1 dr) and enantioselectivities (up to >99% ee). |
| File Format | PDF HTM / HTML |
| DOI | 10.1039/c5ob00708a |
| PubMed reference number | 25877691 |
| Journal | Medline |
| Volume Number | 13 |
| Issue Number | 19 |
| Alternate Webpage(s) | http://www.rsc.org/suppdata/c5/ob/c5ob00708a/c5ob00708a1.pdf |
| Alternate Webpage(s) | http://pubs.rsc.org/en/content/getauthorversionpdf/C5OB00708A |
| Alternate Webpage(s) | https://doi.org/10.1039/c5ob00708a |
| Journal | Organic & biomolecular chemistry |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |