NDLI: Massive Parallel Digital Micro fluidic Biochip Architecture for Automating Large-Scale Biochemistry Assays

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Massive Parallel Digital Micro fluidic Biochip Architecture for Automating Large-Scale Biochemistry Assays

Content Provider	Semantic Scholar
Author	Haddad, Abbas Taajobian, Maryam Jahanian, Ali
Copyright Year	2018
Abstract	Micro/Nano fluidic biochips are used to automate the clinical diagnosis, DNA sequencing, automated drug discovery and real time bio-molecular recognition. One of attractive usages of biochips is Lab-on-chip (LOC). Lab-on-Chip technology is a promising replacement for biomedical and chemical apparatus. Two main types of micro fluidic based biochips are used: continuous-flow based and digital micro fluidic biochips (DMFB). In DMFBs, liquids, in the form of droplets, are controlled independently and concurrently over a two dimensional array of cells (or electrodes).Digital micro fluidic biochips provide high ability to con gure and fault tolerance.In this paper, a new architecture for DMFB with purpose of balancing among the parameters of flexibility, efficiency, cost, and completion time of biological experiments, is presented. In the new architecture, a FPGA-based structure is used, which increase flexibility and paralellizing assay operations. Experiments showthat, the execution time of scheduling, routing, and simulation are improved in comparison with FPPC architecture about 2.54%, 18.76% and 12.52%, respectively in cost of 21% overhead in the number of controlling pins.
Starting Page	3461
Ending Page	3474
Page Count	14
File Format	PDF HTM / HTML
DOI	10.24200/sci.2018.20797
Volume Number	25
Alternate Webpage(s)	http://scientiairanica.sharif.edu/article_20797_0a183a2162024e82e7f86971882d5f06.pdf
Alternate Webpage(s)	http://scientiairanica.sharif.edu/article_20797_f021dcd3ec742f9b3a41de1b03b7f153.pdf
Alternate Webpage(s)	https://doi.org/10.24200/sci.2018.20797
Language	English
Access Restriction	Open
Content Type	Text
Resource Type	Article

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