Comparative Effectiveness of Drug Therapy for Rheumatoid Arthritis and Psoriatic Arthritis in Adults

Content Provider	Semantic Scholar
Author	Donahue, Katrina E. Gartlehner, Gerald Jonas, Daniel E. Lux, Linda J. Thieda, Patricia Jonas, Beth M. Hansen, Richard A. Morgan, Laura C. Sc, Williams Lohr, Kathleen N.
Copyright Year	2007
Abstract	Rheumatoid and psoriatic arthritis are among the most disabling forms of arthritis. Rheumatoid arthritis (RA), which affects 1 percent of the U.S. adult population (or upwards of 2 million individuals), is an autoimmune disease that involves inflammation of the synovium (a thin layer of tissue lining a joint space) with progressive erosion of bone, leading in most cases to misalignment of the joint, loss of function, and disability. The disease tends to affect the small joints of the hands and feet in a symmetric pattern, but other joint patterns are often seen. The diagnosis is based primarily on the clinical history and physical examination. Psoriatic arthritis (PsA) affects fewer people than RA (approximately 1 million people in the United States). PsA is associated with the skin disease psoriasis. It has a highly variable presentation, which generally involves pain and inflammation in joints and progressive joint involvement and damage. Like RA, PsA can be disabling.
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Alternate Webpage(s)	http://www.effectivehealthcare.ahrq.gov/ehc/products/14/70/RheumArthritisExecSum.pdf
Alternate Webpage(s)	https://effectivehealthcare.ahrq.gov/sites/default/files/pdf/rheumatoid-arthritis-2007_research.pdf
Alternate Webpage(s)	http://www.effectivehealthcare.ahrq.gov/ehc/products/14/68/RheumArthritisFinal.pdf
Language	English
Access Restriction	Open
Content Type	Text
Resource Type	Article