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The relationship between right ventricular outflow tract fractional shortening and Pulmonary Embolism Severity Index in acute pulmonary embolism.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Şahan, Ekrem Karamanlıoğlu, Murat Şahan, Suzan Gül, Murat Korkmaz, Ahmet Tüfekçioğlu, Omaç |
| Copyright Year | 2017 |
| Abstract | OBJECTIVE Right ventricular (RV) functions are clinically important in acute pulmonary embolism (APE). Measurement of systolic function of the right ventricular outflow tract (RVOT) with echocardiography is a simple method to evaluate RV function. The aim of this study was to determine the relationship between RVOT systolic function and the Pulmonary Embolism Severity Index (PESI). METHODS A total of 151 patients diagnosed with APE by pulmonary computed tomography angiography or ventilation/perfusion scintigraphy were included. Patients were assigned to 2 groups based on the simplified PESI (sPESI): sPESI <1 (n=85) and sPESI ≥1 (n=66). RV conventional parameters, RVOT dimensions, and fractional shortening (RVOT-FS) were also measured. RESULTS Mean age was similar between sPESI <1 and >1 patients (58.7±12.9 years vs. 61.1±12.7 years, respectively). Frequency of male gender was significantly higher in PESI <1 group (61.2% vs. 40.2%, p=0.013). No significant differences were found between the groups in fasting glucose, serum creatinine, hemoglobin, C-reactive protein, erythrocyte sedimentation rate, troponin, and D-dimer levels, and left ventricular ejection fraction. RVOT-FS was higher in patients with sPESI <1 than in patients with sPESI ≥1 (34.41±3.56 vs. 22.98±4.22), and this difference was significant (p<0.001). Tricuspid annular plane systolic excursion values were lower and pulmonary artery systolic pressure values were higher in the sPESI ≥1 group, which was also statistically significant (p<0.05). Mortality occurred in 7 patients with sPESI <1 and in 16 patients with sPESI ≥1. The mortality rate was higher in patients with lower RVOT-FS, and a RVOT-FS <0.22 predicted mortality with a sensitivity of 54.5% (AUC: 0.674, 95% CI 0.552-0.796; p=0.009). CONCLUSION The RVOT-FS is a noninvasive measurement of RV systolic function, is well-correlated with the sPESI score, and associated with mortality in patients with APE. This easily applied measurement may be used to predict short-term mortality in patients with APE. |
| Starting Page | 709 |
| Ending Page | 714 |
| Page Count | 6 |
| File Format | PDF HTM / HTML |
| DOI | 10.5543/tkda.2017.94694 |
| PubMed reference number | 29226891 |
| Journal | Medline |
| Volume Number | 45 |
| Issue Number | 8 |
| Alternate Webpage(s) | https://www.journalagent.com/tkd/pdfs/TKDA-94694-ORIGINAL_ARTICLE-SAHAN.pdf |
| Alternate Webpage(s) | https://doi.org/10.5543/tkda.2017.94694 |
| Journal | Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |
