Direct electrochemistry of glucose oxidase and sensing glucose using a screen-printed carbon electrode modified with graphite nanosheets and zinc oxide nanoparticles

Content Provider	Semantic Scholar
Author	Karuppiah, Chelladurai Palanisamy, Selvakumar Chen, Shen-Ming Veeramani, Vediyappan Periakaruppan, Prakash
Copyright Year	2014
Abstract	AbstractWe have studied the direct electrochemistry of glucose oxidase (GOx) immobilized on electrochemically fabricated graphite nanosheets (GNs) and zinc oxide nanoparticles (ZnO) that were deposited on a screen printed carbon electrode (SPCE). The GNs/ZnO composite was characterized by using scanning electron microscopy and elemental analysis. The GOx immobilized on the modified electrode shows a well-defined redox couple at a formal potential of −0.4 V. The enhanced direct electrochemistry of GOx (compared to electrodes without ZnO or without GNs) indicates a fast electron transfer at this kind of electrode, with a heterogeneous electron transfer rate constant (Ks) of 3.75 s−1. The fast electron transfer is attributed to the high conductivity and large edge plane defects of GNs and good conductivity of ZnO-NPs. The modified electrode displays a linear response to glucose in concentrations from 0.3 to 4.5 mM, and the sensitivity is 30.07 μA mM−1 cm−2. The sensor exhibits a high selectivity, good repeatability and reproducibility, and long term stability. FigureGraphical representation for the fabrication of GNs/ZnO composite modified SPCE and the immobilization of GOx
Starting Page	1843
Ending Page	1850
Page Count	8
File Format	PDF HTM / HTML
DOI	10.1007/s00604-014-1256-z
Alternate Webpage(s)	https://static-content.springer.com/esm/art:10.1007%2Fs00604-014-1256-z/MediaObjects/604_2014_1256_MOESM1_ESM.pdf
Alternate Webpage(s)	https://doi.org/10.1007/s00604-014-1256-z
Volume Number	181
Journal	Microchimica Acta
Language	English
Access Restriction	Open
Content Type	Text
Resource Type	Article