Geometric and functional architecture of visceral sensory microcircuitry

Content Provider	Semantic Scholar
Author	Negishi, Yoshikatsu Kawai, Yoshinori
Copyright Year	2010
Abstract	hippocampus via the parahippocampal cortical areas including perirhinal cortex, important corticocortical pathways for declarative memory formation. Here, we investigated the intrinsic properties and connection patterns of frontal cortical neurons projecting to the perirhinal regions (FPr cells) by combination of whole cell recording in vitro with retrograde fluorescent labeling from perirhinal subregions and some subcortical structures. FPr cells distributed at multiple layers in specific association with subcortical projection subtypes. The upper layer II/III FPr cells innervated rostral subregion of perirhinal area 35, a little overlapped with amygdala-projecting cells, whereas the upper layer V FPr cells did rostral part of perirhinal area 36, partially sending the collaterals to the contralateral striatum. Both subtypes were distinct from layer V corticothalamic (CTh) cells. Layer II/III FPr cells similarly connected with both layer V FPr and CTh cells, but received backward excitation mostly from layer V FPr cells. These suggest that the neocortex sends information to individual parahippocampal stages via parallel pathways originating from distinct projection subtypes participating in different intraand subcortical pathways.
File Format	PDF HTM / HTML
DOI	10.1016/j.neures.2010.07.1738
Volume Number	68
Alternate Webpage(s)	https://api.elsevier.com/content/article/pii/S0168010210019097
Alternate Webpage(s)	https://www.sciencedirect.com/science/article/pii/S0168010210019097?dgcid=api_sd_search-api-endpoint
Alternate Webpage(s)	https://doi.org/10.1016/j.neures.2010.07.1738
Journal	Neuroscience Research
Language	English
Access Restriction	Open
Content Type	Text
Resource Type	Article