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[Impact of a respiratory disease prevention program in high-risk preterm infants: a prospective, multicentric study].
| Content Provider | Semantic Scholar |
|---|---|
| Author | Bauer, Gabriela Bossi, Lucrecia Santoalla, Marisa Rodríguez, Susana Itzel Pérez Fariña, Diana Speranza, Ana María |
| Copyright Year | 2009 |
| Abstract | UNLABELLED Respiratory tract infections (RTI), especially those caused by Respiratory Syncytial Virus (RSV), are of central concern in high-risk preterm infant care. Prevention programs including new and costly interventions should be evaluated in terms of effectiveness and impact. OBJECTIVES To evaluate feasibility and results of a National Health Ministry pilot program for severe RTI prevention in high-risk infants. METHODS Seven high-risk follow-up clinics from the public healthcare system were selected for a prospective, multicentric study. Between May and September 2007, a pilot program comprising healthcare team training, parental education, RSV passive immunoprophylaxis, RTI patient care end results evaluation was implemented. Indicators were used to evaluate feasibility; effectiveness was estimated comparing study results with two historical controls. RESULTS 183 infants were incorporated, 5 were lost and 1 died from cardiac disease. A RTI management guideline was elaborated among participating centers; parents assisted to educational workshops; palivizumab was given to participating infants up to three doses. RTI hospital admission rate for the study group was 20% (7% RSV-related), compared to 42% (26% RSV-related) and 37% (29% RSV-related) in control groups (p< 0.0001 and p= 0.02, respectively). CONCLUSIONS Program implementation was feasible and readily accepted by healthcare teams. RTI hospital admissions rates, in general and RSV-related, were significatively lower than local previous studies. |
| Starting Page | 275 |
| Ending Page | 280 |
| Page Count | 6 |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | http://www.scielo.org.ar/pdf/aap/v107n2/v107n2a03.pdf |
| PubMed reference number | 19452082v1 |
| Alternate Webpage(s) | https://doi.org/10.1590/S0325-00752009000200004 |
| DOI | 10.1590/S0325-00752009000200004 |
| Journal | Archivos argentinos de pediatria |
| Volume Number | 107 |
| Issue Number | 2 |
| Language | English |
| Access Restriction | Open |
| Subject Keyword | Cessation of life Educational workshop Heart Diseases Hospital admission Immunization Infant Care Premature Obstetric Labor Preterm Infant Respiratory Tract Diseases Respiratory Tract Infections Respiratory syncytial virus palivizumab |
| Content Type | Text |
| Resource Type | Article |
