pH-Responsive, Amphiphilic Core–Shell Supramolecular Polymer Brushes from Cyclic Peptide–Polymer Conjugates

Content Provider	Semantic Scholar
Author	Larnaudie, Sophie C. Brendel, Johannes C. Jolliffe, Katrina A. Perrier, Sébastien
Copyright Year	2017
Abstract	The synthesis and self-assembly of pH-responsive, amphiphilic cyclic peptide–polymer conjugates are described. The design relies on the introduction of a poly(2-(diisopropylamino)ethyl methacrylate) (pDPA) block between the cyclic peptide and a hydrophilic block. These conjugates are disassembled and protonated at low pH but assemble into core–shell nanotubes at physiological pH, as determined by a combination of titration experiments and scattering techniques.
Starting Page	1347
Ending Page	1351
Page Count	5
File Format	PDF HTM / HTML
DOI	10.1021/acsmacrolett.7b00728
Volume Number	6
Alternate Webpage(s)	http://wrap.warwick.ac.uk/100750/1/WRAP-%20pH-Responsive-amphiphilic-core%E2%80%93shell-supramolecular-polymer-brushes-cyclic%20peptide%E2%80%93polymer-Perrier-2017.pdf
Alternate Webpage(s)	https://doi.org/10.1021/acsmacrolett.7b00728
Language	English
Access Restriction	Open
Content Type	Text
Resource Type	Article