Investigations of the Mechanism and Reactivity of Vanadium Bromoperoxidase Isolated from the Marine Brown Alga Ascophyllum nodosum

Content Provider	Semantic Scholar
Author	Walker, Jerrylaine V.
Copyright Year	1998
Abstract	Vanadium bromoperoxidase (V-BrPO) isolated from the marine brown alga Ascophyllum nodosum, is representative of one of two classes of vanadium containing enzymes isolated within the last decade. V-BrPO catalyzes the peroxidative oxidation of chloride, bromide and iodide, which results in the halogenation, or oxidation of a suitable organic substrate or the generation of dioxygen. In this work, the reaction of V-BrPO with the pseudohalide thiocyanate is shown to generate hypothiocyanate and the identity of several short-lived species in this reaction is postulated. V-BrPO is also shown to catalyze the thiocyanation and oxidation of organic substrates. Kinetic parameters for the reactions are also established. Evidence of vanadium- dependent haloperoxidase activity in the red alga Bossiella orbigniana is presented. Furthermore, transition-metal grafted mesoporous silicate materials are found to function as mimics of V-BrPO at neutral pH and in organic solvents. The results of investigations on polunsaturated fatty acid oxidase activity in the red alga B. orbigniana are also presented.
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Language	English
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Content Type	Text
Resource Type	Article