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An Efficient One-Pot Multicomponent Synthesis of Tetracyclic Quinazolino[4,3-b]quinazolines by Sequential C–N Bond Formation and Copper-Mediated Aerobic Oxidative Cyclization
| Content Provider | Semantic Scholar |
|---|---|
| Author | Potuganti, Gal Reddy Indukuri, Divakar Reddy Alla, Manjula |
| Copyright Year | 2018 |
| Abstract | An efficient one-pot synthesis of quinazolino[4,3- b ]quinazoline derivatives has been accomplished, starting from 2-(2-bromophenyl)quinazolin-4(3 H )-one, aldehydes, and various nitrogen sources under aerobic conditions. The multicomponent protocol is mediated by copper(I) salts and involves amination of 2-(2-bromophenyl)quinazolin-4(3 H )-one, followed by condensation with the aldehyde and an oxidative cyclization to give the target compounds in moderate to good yields. |
| Starting Page | 1717 |
| Ending Page | 1722 |
| Page Count | 6 |
| File Format | PDF HTM / HTML |
| DOI | 10.1055/s-0036-1591578 |
| Volume Number | 29 |
| Alternate Webpage(s) | https://www.thieme-connect.com/media/synlett/EFirst/supmat/sup_st-2018-d0123-l_10-1055_s-0036-1591578.pdf |
| Alternate Webpage(s) | https://doi.org/10.1055/s-0036-1591578 |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |
