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The characterization of neutralizing and non-neutralizing monoclonal antibodies against equid herpesvirus type 1.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Sinclair, Roderick Cook, R. Mumford, Jennifer A. |
| Copyright Year | 1989 |
| Abstract | Seven monoclonal antibodies (MAbs) were produced which recognized equid herpesvirus type 1 (EHV-1). Three MAbs neutralized the subtype 1 virus (strain Army 183) in the presence of complement, but did not neutralize the subtype 2 virus (strain MD). All three MAbs immunoprecipitated an Mr 83K glycoprotein from a detergent-solubilized virion envelope preparation of the subtype 1 virus. The target antigens of the four non-neutralizing MAbs (6F11, 2A4, 1F10 and 8D9) were identified by immunoblotting against purified EHV-1 virions and had respective apparent Mr values of greater than 205K, greater than 205K, 97K and 13K. |
| File Format | PDF HTM / HTML |
| DOI | 10.1099/0022-1317-70-2-455 |
| PubMed reference number | 2543748 |
| Journal | Medline |
| Volume Number | 70 |
| Part | 2 |
| Alternate Webpage(s) | http://www.microbiologyresearch.org/docserver/fulltext/jgv/70/2/JV0700020455.pdf?accname=guest&checksum=562CD15473F7B8D7B147C3B698138F67&expires=1544685958&id=id |
| Alternate Webpage(s) | http://citeseerx.ist.psu.edu/viewdoc/download;jsessionid=F623929D031D3936F3B608EF68796BB1?doi=10.1.1.544.8068&rep=rep1&type=pdf |
| Alternate Webpage(s) | https://www.microbiologyresearch.org/docserver/fulltext/jgv/70/2/JV0700020455.pdf?accname=guest&checksum=06ADEC3F64E787F941040DFE1A56F637&expires=1549220909&id=id |
| Alternate Webpage(s) | https://doi.org/10.1099/0022-1317-70-2-455 |
| Journal | The Journal of general virology |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |