United States Patent ( 19 ) Pryce et al . 54 PROCESS FOR PREPARING

Content Provider	Semantic Scholar
Copyright Year	2017
Abstract	in which Rand Reach independently represent a C1-6 alkyl or C6-12 aryl group, and R represents an alkyl, aryl, aralkyl, heterocyclic or carboxylic group, which process comprises reacting a carboxylic acid having the general formula I in which R represents a hydroxy group with a lithium compound to form the corre sponding lithium salt of the carboxylic acid; reacting the lithium salt so-obtained with thionyl chloride to yield an acyl chloride having the general formula I in which R represents a chlorine atom; reacting the acyl chloride so-obtained with a secondary amine to yield an amide having general formula I in which R represents a secondary amino group; and reacting the amide so obtained with an organonetallic reagent to yield the ketone having general formula I.
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Language	English
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Content Type	Text
Resource Type	Patent