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Outbreak of poliomyelitis in Hispaniola associated with circulating type 1 vaccine-derived poliovirus.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Kew, Olen Morris-Glasgow, Victoria Landaverde, Mauricio Burns, Cara Shaw, Jing Garib, ZacarÃas André, Jean Blackman, Elizabeth Jorba, Jaume Sutter, Roland Tambini, Gina Venczel, Linda Pedreira, Cristina Laender, Fernando Shimizu, Hiroyuki Yoneyama, Tetsuo Miyamura, Tatsuo Avoort, Harrie G. A. M. Van Der Oberste, Max Kilpatrick, David Pallansch, Mark |
| Copyright Year | 2002 |
| Abstract | An outbreak of paralytic poliomyelitis occurred in the Dominican Republic (13 confirmed cases) and Haiti (8 confirmed cases, including 2 fatal cases) during 2000-2001. All but one of the patients were either unvaccinated or incompletely vaccinated children, and cases occurred in communities with very low (7 to 40%) rates of coverage with oral poliovirus vaccine (OPV). The outbreak was associated with the circulation of a derivative of the type 1 OPV strain, probably originating from a single OPV dose given in 1998-1999. The vaccine-derived poliovirus associated with the outbreak had biological properties indistinguishable from those of wild poliovirus. |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | https://www.med-ed.virginia.edu/Courses/micro/pdf/ref_added_2007/PolioOutbreak.pdf |
| Alternate Webpage(s) | https://www.med-ed.virginia.edu/courses/micro/pdf/poliokew.pdf |
| PubMed reference number | 11896235v1 |
| Volume Number | 296 |
| Issue Number | 5566 |
| Journal | Science |
| Language | English |
| Access Restriction | Open |
| Subject Keyword | Community Oral Poliovirus Vaccine Patients Poliomyelitis Poliovirus Vaccines |
| Content Type | Text |
| Resource Type | Article |
