NDLI: Species distribution and antifungal susceptibility of Candida species causing candidaemia in a Thai university hospital during year 2006-2010

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Species distribution and antifungal susceptibility of Candida species causing candidaemia in a Thai university hospital during year 2006-2010

Content Provider	Semantic Scholar
Author	Ankkananukul, K. Homkaew, A. Chongtrakool, Piriyaporn Santanirand, Pitak
Copyright Year	2011
Abstract	Results From a total of 887 isolates, Candida albicans remains a major pathogen accounted for 50.3%, followed by C. tropicalis(27.4%), C. parapsilosis (12.5%), C.guilliermondii (6%), C. glabrata (1.8%), C. krusei (0.23%), C. rugosa (0.23%), and unidentified species(1.6%). From a total of 103 C. albicans, amphotericin B MIC ranged from 0.016-1ug/ml whereas fluconazole MIC ranged were between 0.023 to > 256ug/ml. Other species tested were C. tropicalis (73 strains) which yielded MIC range of 0.19-2ug/ml for amphotericin B and 0.5>256 ug/ml for fluconazole. 34 strains of C. parapsilosis gave amphotericin B ranged from 0.023-16ug/ml and 0.094->256 for fluconazole. Conclusion C. albicans remains the most prevalence Candida species causing candidaemia followed by C. tropicalis, C. parapsilosis and C. guilliermondii. Those non-albicans Candida seemed to express decrease susceptibility to both major antifungal agents like amphotericin B and fluconazole whereas a small number of C. albicans gave high MIC to fluconazole.
Starting Page	P206
Ending Page	P206
Page Count	1
File Format	PDF HTM / HTML
Alternate Webpage(s)	https://bmcproc.biomedcentral.com/track/pdf/10.1186/1753-6561-5-S6-P206?site=bmcproc.biomedcentral.com
Alternate Webpage(s)	http://ftp.ncbi.nlm.nih.gov/pub/pmc/55/e1/1753-6561-5-S6-P206.PMC3239629.pdf
PubMed reference number	3239629
Volume Number	5
Language	English
Access Restriction	Open
Subject Keyword	Amphotericin B Antifungal Agents Candida (fungus) Candida albicans Ag:Titr:Pt:Ser:Qn:LA Candida albicans reaction wheal^1D post 50 ug Candida albicans ID:Diam:Pt:Skin:Qn Candida parapsilosis Candida rugosa Candida tropicalis Candidemia Fluconazole Hospitals, University Pathogenic organism negative regulation of reactive oxygen species biosynthetic process
Content Type	Text
Resource Type	Article

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