NDLI: Glycated Hemoglobin and All-Cause Mortality in Korean Type 2 Diabetes

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Glycated Hemoglobin and All-Cause Mortality in Korean Type 2 Diabetes

Content Provider	Semantic Scholar
Author	An, Mi Suk Kim, Sun A. Lee, Jun-Ho Choi, Seong-Woo Shin, Min Ho
Copyright Year	2017
Abstract	The purpose of this study was to evaluate the association between glycated hemoglobin (HbA1c) and all-cause mortality in type 2 diabetes mellitus. We conducted a community-based prospective cohort study of 352 type 2 diabetic patients aged 30-92 who participated in a community diabetes complications screening program in Gokseng-gun, Jeollanamdo, Korea. HbA1c levels were categorized as <6.5%, 6.5-6.9%, 7.0-7.9%, 8.0-8.9% and ≥9.0%. Patients were followed up on for a mean of 6.9 years. The Cox proportional hazards model was used to evaluate the relationship between HbA1c levels and all-cause mortality. During the mean follow-up period of 6.9 years, 77 patients (21.9%) died. A J-shaped association was found between HbA1c and all-cause mortality, with the lowest mortality at 6.5-6.9% of HbA1c levels. Compared to patients with HbA1c of 6.5-6.9%, patients with <6.5%, 7.0-7.9%, 8.0-8.9% and ≥9.0% had an adjusted hazard ratio (95% confidence interval) for all-cause mortality of 1.71 (0.76-3.84), 1.23 (0.53-2.82), 1.32(0.51-3.44) and 2.66 (1.01-7.02), respectively. We found a J-shaped association between glycated hemoglobin and all-cause mortality in Korean type 2 diabetic patients.
Starting Page	223
Ending Page	228
Page Count	6
File Format	PDF HTM / HTML
Alternate Webpage(s)	https://www.cmj.ac.kr/Synapse/Data/PDFData/1057CMJ/cmj-53-223.pdf
PubMed reference number	29026711v1
Alternate Webpage(s)	https://doi.org/10.4068/cmj.2017.53.3.223
DOI	10.4068/cmj.2017.53.3.223
Journal	Chonnam medical journal
Volume Number	53
Language	English
Access Restriction	Open
Subject Keyword	Central Diabetes Insipidus Cessation of life Confidence Intervals Diabetes Mellitus Diabetes Mellitus, Insulin-Dependent Diabetes Mellitus, Non-Insulin-Dependent Glycosylated hemoglobin A Hazard Ratio Patients
Content Type	Text
Resource Type	Article

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