Loading...
Please wait, while we are loading the content...
Similar Documents
Beneficial effect of dietary wheat glycolipids on cecum short-chain fatty acid and secondary bile acid profiles in mice.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Sugawara, Tatsuya Miyazawa, Teruo |
| Copyright Year | 2001 |
| Abstract | In the present study, to explore the beneficial effect of dietary galactoglycerolipids on the lower digestive tract environment, male BALB/c mice were fed a 5% wheat glycolipid, fiber-free diet, or the standard AIN diet for 3 wk. The wheat glycolipid composition was digalactosyldiacylglycerol 51.6%, ceramide monohexoside 6.6%, acylated sterylglucoside 3.4%, and other lipids 22.2%, (mostly phospholipids). Cecum and colon weights and colonic crypt depth were significantly greater in the glycolipid-diet mice relative to groups fed the other two diets. Furthermore, in the cecum, propionate. butyrate, and total short-chain fatty acids, concentrations were significantly greater in the glycolipid-diet mice than others were, and correlated with the observed increased lower digestive tract (cecum and colon) weights and colonic crypt depth. The cecal lithocholic acid/deoxycholic acid ratio, a risk index for colorectal cancer, was significantly lower in the glycolipid-diet mice than in the other two dietary groups. These results suggest that the dietary supplementation of plant-source galactoglycerolipids may contribute to improving the lower digestive tract environment. |
| Starting Page | 299 |
| Ending Page | 305 |
| Page Count | 7 |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | https://www.jstage.jst.go.jp/article/jnsv1973/47/4/47_4_299/_pdf |
| PubMed reference number | 11767211v1 |
| Volume Number | 47 |
| Issue Number | 4 |
| Journal | Journal of nutritional science and vitaminology |
| Language | English |
| Access Restriction | Open |
| Subject Keyword | Acyl-Homoserine Lactones Bile Acids Bile fluid Butyrates Cecum Ceramides Colon structure (body structure) Colorectal Carcinoma Crypt Deoxycholic Acid Dietary Supplementation Digestion Fatty Acids Fatty Acids, Volatile Gastrointestinal system Gastrointestinal tract structure Glycolipids Lithocholic Acid Propionates Thioctic Acid Tissue fiber Weight anal dysplasia digalactosyldiacylglycerol |
| Content Type | Text |
| Resource Type | Article |
