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Microfluidic synthesis of cell-type-specific artificial extracellular matrix hydrogels.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Allazetta, Simone Hausherr, Tanja Cloé Lutolf, Matthias P. |
| Copyright Year | 2013 |
| Abstract | Droplet microfluidic technology is applied for the high-throughput synthesis via Michael-type addition of reactive, micrometer-sized poly(ethylene glycol) (PEG) hydrogels ("microgels") with precisely controlled dimension and physicochemical properties. A versatile chemical scheme is used to modify the reactive PEG microgels with tethered biomolecules to tune their bioactive properties for the bioreactor culture and manipulation of various (stem) cell types. |
| Starting Page | 111 |
| Ending Page | 123 |
| Page Count | 13 |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | https://infoscience.epfl.ch/record/185133/files/Microfluidic%20Synthesis%20of%20Cell-Type-Specific%20Artificial%20Extracellular%20Matrix%20Hydrogels.pdf |
| PubMed reference number | 23439131v1 |
| Alternate Webpage(s) | https://doi.org/10.1021/bm4000162 |
| DOI | 10.1021/bm4000162 |
| Journal | Biomacromolecules |
| Volume Number | 14 |
| Issue Number | 4 |
| Language | English |
| Access Restriction | Open |
| Subject Keyword | Bioreactors Extracellular Matrix Hydrogels Microfluidics Polyethylene Glycols |
| Content Type | Text |
| Resource Type | Article |