NDLI: Hepatoprotective effect of aqeous methanolic extract of Rumex dentatus in paracetamol-induced hepatotoxicity in mice

Content Provider	Semantic Scholar
Author	Saleem, Mohammad Ahmed, Bilal Ashfaq Karim, Mahrukh Ahmed, Shahzad Ahmad, M. Sajid Aqeel Qadir, Muhammad Imran Syed, Nawazish-I-Husain
Copyright Year	2014
Abstract	Rumex dentatus is well known plant of Polygonaceae family which is widely used in traditional medicine to treat gastrointestinal tract. R. dentatus at doses 250 and 500 mg/kg significance decreased (p<0.001) the elevated level of ALT, AST, ALP and bilirubin induced by paracetamol and results are comparable (p<0.001) with silymarin. The results were supported by histopathological investigations, phytochemical screening and detection of hepatoprotective active constituents e.g quercetin, kaempferol, myricetin by HPLC. So, it is concluded that R. dentatus has hepatoprotective effect against paracetamol liver damage in mice. DOI: http://dx.doi.org/10.3329/bjp.v9i3.18874
Starting Page	284
Ending Page	289
Page Count	6
File Format	PDF HTM / HTML
DOI	10.3329/bjp.v9i3.18874
Volume Number	9
Alternate Webpage(s)	https://www.banglajol.info/index.php/BJP/article/download/18874/13472
Alternate Webpage(s)	https://doi.org/10.3329/bjp.v9i3.18874
Language	English
Access Restriction	Open
Content Type	Text
Resource Type	Article

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