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Three novel polymorphic microsatellite markers for the glaucoma locus GLC1B by datamining tetranucleotide repeats on chromosome 2p12-q12
| Content Provider | Semantic Scholar |
|---|---|
| Author | Murga-Zamalloa, Carlos A. Guevara-Fujita, María Luisa Estrada-Cuzcano, Alejandro Fujita, Ricardo |
| Copyright Year | 2009 |
| Abstract | In order to identify new markers around the glaucoma locus GLC1B as a tool to refine its critical region at 2p11.2-2q11.2, we searched the critical region sequence obtained from the UCSC database for tetranucleotide (GATA)n and (GTCT)n repeats of at least 10 units in length. Three out of four potential microsatellite loci were found to be polymorphic, heterozygosity ranging from 64.56% to 79.59%. The identified markers are useful not only for GLC1B locus but also for the study of other disease loci at 2p11.2-2q11.2, a region with scarcity of microsatellite markers. |
| Starting Page | 720 |
| Ending Page | 722 |
| Page Count | 3 |
| File Format | PDF HTM / HTML |
| PubMed reference number | 21637444 |
| DOI | 10.1590/s1415-47572009005000093 |
| Journal | Genetics and molecular biology |
| Volume Number | 32 |
| Alternate Webpage(s) | http://ftp.ncbi.nlm.nih.gov/pub/pmc/8d/0c/gmb-32-4-720.PMC3036884.pdf |
| Alternate Webpage(s) | http://www.scielo.br/pdf/gmb/v32n4/2008-289.pdf |
| Alternate Webpage(s) | https://doi.org/10.1590/S1415-47572009005000093 |
| Language | English |
| Access Restriction | Open |
| Subject Keyword | Glaucoma Heterozygote Search - action Short Tandem Repeat VENTRICULAR TACHYCARDIA, CATECHOLAMINERGIC POLYMORPHIC, 1 (disorder) |
| Content Type | Text |
| Resource Type | Article |
