NDLI: Q M ] 2 8 A ug 2 01 3 Growth and form of melanoma cell colonies

Content Provider	Semantic Scholar
Author	Baraldi, Massimiliano Maria Alemi, Alexander A. James, Philip Sethna Caracciolo, Sergio Porta, Caterina A. M. La Zapperi, Stefano
Copyright Year	2013
Abstract	We study the statistical properties of melanoma cells colonies grown in vitro analyzing the results of crystal violet assays at different concentrations of initial plated cells and for different growth times. The distributions of colony sizes is well described by a continuous time branching process. To characterize the shape fluctuations of the colonies, we compute the distribution of eccentricities. The experimental results are compared with numerical results for models of random division of elastic cells showing that experimental results are best reproduced by restricting cell division to the outer rim of the colony. Our results serve to illustrate the wealth of information that can be extracted by a standard experimental method such as the crystal violet assay.
File Format	PDF HTM / HTML
Alternate Webpage(s)	https://www.isi.it/wp_blobs/publication/document/1308_6037v1_1390994694.pdf
Language	English
Access Restriction	Open
Content Type	Text
Resource Type	Article

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