Loading...
Please wait, while we are loading the content...
Similar Documents
A High-sensitivity On-chip Fluorescence Detection for Lab-on-a-chip
| Content Provider | Semantic Scholar |
|---|---|
| Author | Shuai, Yun Banerjee, Ansuman Klotzkin, David Papautsky, Ian |
| Copyright Year | 2008 |
| Abstract | In this paper, we present an improved high-sensitivity approach for on-chip fluorescence-based measurements for disposable lab-on-a-chip (LOC). We use a bilayer organic photodiode (OPD), cross-polarization, and improved integration to enhance Rhodamine 6G limit of detection (LOD) to 10 nM, which is a 10-100 fold improvement over current reports in literature. A prototype system was fully characterized experimentally, and an analytical model was developed by modifying the Beer Lambert’s Law. We expect the developed approach to envisage numerous applications in point-of-care diagnostics and on-site environmental testing. |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | http://www.rsc.org/binaries/LOC/2008/PDFs/Papers/095_0550.pdf |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |
