2428 Microinjection of calcitonin gene-related peptide into the ventromedial hypothalamic nucleus activates heat production

Content Provider	Semantic Scholar
Author	Kobayashi, Akiko Osaka, Toshimasa Inoue, Shuji Kimura, Shuichi
Copyright Year	1997
Abstract	TAKAO NAKAMURAl, MASAHIRO SHIMONOl, MASATAKA KUSUNOK12, ICHIRO MINEJIMA’, TSUTOMU HARA2, KOICHI KAWAHARAl In our previous works, temporary decrease in blood glucose level, showing the increase in muscle glucose uptake, was observed immediately after the onset of tetanic but not rhythmic contraction of hindlimb muscle induced by electrical stimulation of the sciatic nerve in rats, which suggested the existence of neural control system of muscle glucose uptake, as one of the non-insulin mediated glucose uptake mechanisms, and that the control system could include the sympathetic nervous system. Therefore, in the present study, muscle sympathetic nerve activity (MSNA) in the ipsilateral sciatic nerve was directly measured by microneurography, before and after the hindlimb muscle contraction. The results showed that MSNA increased in the period during which muscle glucose uptake increased, supporting the possible involvement of the sympathetic nervous system in the non-insulin mediated neural control system of muscle glucose uptake.
File Format	PDF HTM / HTML
DOI	10.1016/S0168-0102(97)90786-0
Alternate Webpage(s)	https://api.elsevier.com/content/article/pii/S0168010297907860
Alternate Webpage(s)	https://www.sciencedirect.com/science/article/pii/S0168010297907860?dgcid=api_sd_search-api-endpoint
Alternate Webpage(s)	https://doi.org/10.1016/S0168-0102%2897%2990786-0
Volume Number	28
Journal	Neuroscience Research
Language	English
Access Restriction	Open
Content Type	Text
Resource Type	Article