Universidade Federal Do Rio Grande Do Sul Faculdade De Medicina Programa De Pós-graduação Em Medicina: Ciências Médicas Avaliação Do Efeito Da Terapia Ocupacional No Perfil Funcional De Pacientes Com Diagnóstico De Doença De Machado-joseph

Content Provider	Semantic Scholar
Author	Silva, Renata Rocha Da
Copyright Year	2008
Abstract	Purpose: Occupational therapy (OT) is nowadays part of the clinical rehabilitation of progressive genetic neurodegenerative diseases, such as spinocerebellar ataxias; however, its effects have never been measured in these diseases. Our aim was to investigate the effect of OT on both physical disabilities and depressive symptoms of spinocerebellar ataxia type 3 (SCA3) patients. Methods: molecularly diagnosed SCA3 patients older than 18 years were invited to participle in the study. Disability, as evaluated by “functional independence measurement” (FIM) and Barthel incapacitation score, Hamilton Rating Scale for Depression, and “WHOQOL-BRIEF” were measured at baseline and after 3 and 6 months of treatment. Results: Twenty-six patients agreed in participate in the study. After 6 months on OT, disability scores and quality of life were stable, and the Hamilton scores for depression improved. No association was found between these endpoints and CAGn, age, age of onset, or neurological scores at baseline. Conclusions: OT improved depressive symptoms. Although the possibly temporary stabilization of the downhill disabilities as an effect of OT remains to be established, the clear effect on depressive symptoms confirms the recommendation of OT to any given patient with SCA3 or a spinocerebellar ataxia.
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Alternate Webpage(s)	https://www.lume.ufrgs.br/bitstream/handle/10183/15225/000673388.pdf?sequence=1
Language	English
Access Restriction	Open
Content Type	Text
Resource Type	Article